Search on: CGMP DEPENDENT PROTEIN KINASE IALPHA 
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Descriptor English:   Cyclic GMP-Dependent Protein Kinase Type I 
Descriptor Spanish:   Proteína Quinasa Dependiente de GMP Cíclico Tipo I 
Descriptor Portuguese:   Proteína Quinase Dependente de GMP Cíclico Tipo I 
Synonyms English:   PKGI beta
PKGIalpha
PKGIbeta
Protein Kinase G I alpha
cGK-Ialpha
cGMP-Dependent Protein Kinase I
cGMP-Dependent Protein Kinase Ialpha
cGMP-Dependent Protein Kinase Ibeta
Cyclic GMP Dependent Protein Kinase Type I
cGMP Dependent Protein Kinase I
cGMP Dependent Protein Kinase Ialpha
cGMP Dependent Protein Kinase Ibeta  
Tree Number:   D08.811.913.696.620.682.700.150.150.500
D12.644.360.200.150.500
D12.776.476.200.150.500
Definition English:   A cyclic GMP-dependent protein kinase subtype that is expressed in SMOOTH MUSCLE tissues and plays a role in regulation of smooth muscle contraction. Two isoforms, PKGIalpha and PKGIbeta, of the type I protein kinase exist due to alternative splicing of its mRNA. 
History Note English:   2013 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   54933 
Unique Identifier:   D062965 

Occurrence in VHL: 		 

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